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Episode #7: Large Viruses as Gene Therapy Platforms

Episode #7: Large Viruses as Gene Therapy Platforms

Johns Hopkins Center for Health Security... · 20:10 · 4,814 plays

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Dr. Lauren Oldfield, Director of Synthetic Genomics, Replay April 17, 2023 In this episode, we discuss efforts to develop large DNA viruses, such as herpesviruses, as vectors to deliver gene therapies, including advantages over other types of pathogen platforms. Notably, large viruses enable the delivery of larger genes for therapeutic purposes, and the characteristics of herpes simplex viruses (HSV) can allow gene therapies to be delivered over longer periods of time.

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